Computer Aided Drug Designing

Good News For Researchers !!!
A workshop for PhD students and post-doctoral researchers coming with their own real data sets will get the training and their data analysis done at considerable discount. After this course they will be able to analyze their own data and create ready-to-publish graphics
Goals :
Computer aided drug designing workshop will provide hands on training on structure and target based design, molecular modeling, quantum mechanics, drug likeness properties, QSAR and pharmacokinetic and dynamics

Participants will be introduced with its applicability to real-time data analysis problem. All our training content is as per industrial requirement and 100% practical exposure which will help candidate to make their better career in the field of bioinformatics.

Hurry up and register soon...To become expert in Bioinformatics !

## 10% Discount if you register before 15th December, 2024. Hurry up!!

Computer Aided Drug Designing(CADD) Training Program

CADD Training Information

Application

CADD

Period of Training

Offline - 21 Days Training [ 2 Hours Daily [ Monday To Friday ] ]
/ Online - 21 Days Training [ 2 Hours Daily [ Monday To Friday ] ]

Course Fee

For course fee please request you to contact us at info@arraygen.com

Training Starting Date

Our training is one to one and training can also be started anytime and anydate as per the candidate convenience. ** Weekend Batches are also available as per the request

Training Slots

Our working Time is 9:00 AM to 6:00 PM Indian Time Available slots - 9:00 AM to 11:00 AM / 11:00 AM to 1:00 PM / 2:00 PM to 4:00 PM / 4:00 PM to 6:00 PM

Training Mode

Online/Offline
Online(For online training candidate have to install Skype and AnyDesk / ZOOM )(it is same like offline) Offline(For offline training candidate have to come to head office Pune and bring their own laptop).
All our training is one to one and 100% focus with individual candidate which provides 100% learning.

Module - I

Ligand Based Drug Design(Pharmacophore design)

Topics

  • Introduction to Bioinformatics and Understanding Genomics, Proteomics and CADD
  • Databases(NCBI- GeneDB and ProteinDB,PubMed,Uniprot,KEGG Pathway,PubChem,Drug Bank,RCSB-PDB,ZINC,ModBase)
  • Understanding file formats (sdf,mol,pdb)
  • 1D Line Notations (SMILES, InChI)
  • Sequence Based Search Tool [BLAST]
  • Linux Installation + Commands + CADD Tools installation [Gromacs, etc.]
  • Python Programming for handling large Data or Automation process
  • Collection of primary key data
  • Pharmacophore preparation
  • Chemical Library preparation based on Pharmacophore
  • Insilico Screening (ADME)
  • Toxicity screening
  • QSAR (Quantitative structure-activity relationship) Model

Module - II

Structure based Drug Design (target-ligand docking)

Topics

  • Introduction to Structure based Drug Design and process layout of Docking
  • Data mining, literature study and acquisition of target structure
  • Comparative modelling of protein (Homology modelling) *target structure not available
  • Server based –PHYRE, RaptorX, SWISSMODEL, I-TASSER, etc.
  • Ramachandran plot assessment(RAMPAGE,Pdbsum,Procheck)
  • Active site/ Pocket identification –MetaPocket,CastP,Active site identification using PyMol
  • Molecular Docking *using AutoDock vina/AutoDock Tools/PyRx (For docking of multiple ligands)
  • Protein and ligand preparation
  • Setting grid parameters and Docking parameters
  • Docking analysis (based on binding energy, Hydrogen bond interactions, electrostatic interactions, hydrophobic interactions, etc.)
  • BINANA (BINding ANAlyser)
  • Pdbsum for visualising protein-ligand interactions
  • Building protein-ligand complex and visualization(publication standard)
  • Visualisation of GWAS results (Manhattan plot and QQ-Plot)
  • Report construction

Module - III

Molecular Dynamics(MD) Simulation

Topics

  • Introduction to Molecular Dynamics Simulation
  • Basic Principles of Molecular Dynamics Simulations(Non-bonded interactions,Bonding Potentials, Force fields)
  • Molecular Dynamics Simulation using GROMACS/VMD-NAMD
  • Installation of softwares required for simulations
  • Definition of molecular structures, Force field and topology,Preparation of files
  • Simulation(Energy Minimization,Heating,Equilibration,Production)
  • Analysis of results
  • Simulating many molecules

Eligibility

B.Sc/B.Tech/M.Tech. / M.Sc. /Ph.D /PostDocs/Any Life Sciences in Biological Science, Computer science, Pharmacy, Agriculture, Biotechnology, Molecular biology, Medicine, clinical research and other relevant Qualification in the life sciences areas are eligible.

Certificate

All the participants will receive certificates on successful completion of training

Place

ArrayGen, Pune, India

Contact

info@arraygen.com

Send Enquiry
Registration is now open please request to sign up to reserve your place! If you are interested, you can mail us at info@arraygen.com We hope to see you in this new year. Dont miss this opportunity.